Research Trial for Myelofibrosis (11 Months)

Adults (male or female) aged 18 years and older with a diagnosis of primary or secondary myelofibrosis (MF), may qualify to participate. Primary myelofibrosis (PMF) is defined as a progressive, chronic disease in which the bone marrow is replaced by fibrous tissue. This disease is marked by an enlarged spleen and progressive anaemia. Secondary myelofibrosis (SMF) occurs in patients with essential thrombocythemia (ET) or polycythaemia vera (PV) who acquire features of MF; they are then called post-Polycythaemia Vera Myelofibrosis (post-PV MF), or post-Essential Thrombocytosis Myelofibrosis (post-ET MF). Individuals must not currently be taking a Janus kinase (JAK) inhibitor (e.g. ruxolitinib or fedratinib) within 2 weeks of enrollment.

Participants will receive investigational oral medication (active study drug). Investigational medication and study-related care will be provided at no cost. Reimbursement for study-related expenses will also be provided.

Study participation will last about 11 months and involve about 10 visits to the study centre.

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  • At this time there are no other studies for this condition. Please register to be contacted about upcoming studies for this condition.

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Why Take Part In a Clinical Study?

Regulatory agencies like Health Canada, Australia's Therapeutic Goods Administration and the FDA require that Clinical Research Trials be conducted in order to develop new treatments, preventions and devices for diseases or conditions. Clinical Research Trials are also referred to as Clinical Studies or Clinical Trials. read more