Nail and Body Psoriasis Research Trial (76 Weeks)

Adults aged 18 years or older with chronic moderate to severe plaque-type psoriasis for at least 6 months, may qualify to participate. Individuals must have moderate to severe nail psoriasis AND moderate to severe plaque psoriasis on the body. Psoriatic involvement of 10% or more body surface area (BSA) is required in addition to nail involvement. Participants must be considered candidates for systemic therapy, meaning psoriasis is inadequately controlled by topical treatments (corticosteroids), and/or phototherapy, and/or previous systemic therapy.

Participants will receive investigational medication (active study drug) or placebo in Part 1, via subcutaneous injection. In Part 2, those who initially received placebo will be switched over to receive active study drug. Study medication and study-related procedures will be provided at no cost. Reimbursement for study-related expenses will also be provided.

Study participation will last about 76 weeks and involve about 15 visits to the study centre.

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Why Take Part In a Clinical Study?

Regulatory agencies like Health Canada, Australia's Therapeutic Goods Administration and the FDA require that Clinical Research Trials be conducted in order to develop new treatments, preventions and devices for diseases or conditions. Clinical Research Trials are also referred to as Clinical Studies or Clinical Trials. read more