Comparator Trial for Plaque Psoriasis (68 Weeks)

Adults aged 18-75 years old with stable moderate to severe plaque psoriasis for at least 6 months, may qualify to participate. Individuals must have psoriatic involvement of 10% or more body surface area. Previous failure, inadequate response, intolerance, or contraindication to at least 1 conventional anti-psoriatic systemic therapy is required. There must also be no known history of latent or active tuberculosis (TB); testing will occur at screening.

Participants will be part of one of two groups: the continued-use group (receiving ustekinumab) OR the switching group (receiving investigational medication (active study drug) and ustekinumab), via subcutaneous injection. Study medication and study-related assessments will be provided at no cost. Reimbursement for study-related expenses will also be provided.

Study participation will last about 68 weeks and involve about 14 visits to the study centre.

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Why Take Part In a Clinical Study?

Regulatory agencies like Health Canada, Australia's Therapeutic Goods Administration and the FDA require that Clinical Research Trials be conducted in order to develop new treatments, preventions and devices for diseases or conditions. Clinical Research Trials are also referred to as Clinical Studies or Clinical Trials. read more