Symptomatic Dilated Cardiomyopathy Study

Adults aged 18 and older who have symptomatic dilated cardiomyopathy, may qualify to participate. Gene positive for a deleterious mutation in the LMNA gene will be determined.

Individuals must have an ICD (implantable cardioverter defibrillator) implanted at least 4 weeks prior to start of study treatment, or a CRT-D (cardiac resynchronization therapy defibrillator) initiated at least 6 months prior to start of study treatment.

Participants will receive investigational oral medication (either active study drug or placebo) during the double-blind treatment period. All participants will receive active study drug during the open-label treatment period.

Study medication and study-related care will be provided at no cost. The length of study participation will vary among individuals but could last approximately 1 year.

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Similar Studies

  • At this time there are no other studies for this condition. Please register to be contacted about upcoming studies for this condition.

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If there are no active studies for your condition, we will keep your information and contact you when a new study starts in your area.

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Why Take Part In a Clinical Study?

Regulatory agencies like Health Canada, Australia's Therapeutic Goods Administration and the FDA require that Clinical Research Trials be conducted in order to develop new treatments, preventions and devices for diseases or conditions. Clinical Research Trials are also referred to as Clinical Studies or Clinical Trials. read more